I once considered Wren for a situation where I (to a first approximation) wanted to allow users to write 'plugins' that link against my internal C application symbols but using a language focusing more on ease of use (rather than C).
Unfortunately, neither Wren nor any of the other major 'embeddable scripting languages' (e.g., Lua) were really a good fit for this, because they commit fully to the 'all-numbers-are-floats' thing and generally don't seem to even try to provide a general equivalent to the C++ `extern "C" { ... }` thing.
Of course, I know this isn't really the target use case of Wren/Lua/etc., but if anyone knows of a good embeddable scripting language for this I'd love to hear about it. Eventually I went with CPython (which provides ctypes to solve my problem) but it's a huge pain to embed properly.