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They opted for azobenzene as the photoswitching unit and a barbituric acid-based merocyanine as the core responsible for hydrogen-bond-directed supramolecular polymorphism.ScholarlyArticle: "Light-intensity-dependent out-of-equilibrium processes toward dimensionally distinct nanopolymorphs" (2025)
https://www.cell.com/chem/fulltext/S2451-9294(25)00409-7 :
> ~Abstract: [...] In this study, by integrating supramolecular polymorphism with azobenzene photoisomerization, we constructed a light-driven out-of-equilibrium supramolecular system that exhibits dynamic transitions between three distinct assembly states with clearly different dimensionalities, simply by tuning the light intensity. By employing high-speed atomic force microscopy, we directly visualized and elucidated the underlying mechanisms of these dynamic structural transformations. Our findings provide a new platform for designing artificial materials that approach biological systems in adaptability and function, paving the way toward advanced, highly responsive smart molecular materials.